701. Psychology, Behavior and Neurobiology - mental health Scientific Abstract

3454 - Assessing The Relationship Between Depression-related Symptoms And Post-concussion Clinical Outcomes

Abstract

Concussive injury and depression affect millions of individuals each year and are connected through common overlapping symptoms. PURPOSE: Aim 1 was to establish an association between post-concussion depression-related symptoms and post-concussion symptoms, balance performance, vestibular function, and executive function. Aim 2 was to further establish the relationship between concussion history and post-concussion depression-related symptoms, concussion symptoms, and mood disturbance. METHODS: 164 concussed individuals (mean age=14.52±3.51 years, 50.61% male, mean time from injury=18.24±13.60) were included in this analysis. Depression-related symptoms were quantified using the Beck Depression Inventory (BDI-II) and post-concussion symptoms using the Rivermead Post-Concussion Symptoms Questionnaire (RPQ). Clinical post-concussion assessments utilized were the modified Balance Error Scoring System (mBESS), Vestibular/Ocular-Motor Screening (VOMS), and, for adolescent patients, the Behavior Rating Inventory of Executive Function (BRIEF). Mood disturbance was quantified using the Profile of Mood States (POMS). mBESS, VOMS, RPQ, and BRIEF were measured against BDI-II scores using Pearson Correlation and Linear Regression analyses. BDI-II, POMS, and RPQ scores were analyzed based on concussion history using Wilcoxon Rank-Sum Tests. RESULTS: As depression-related symptoms increased, post-concussion symptoms (p<0.001, r=0.68) and VOMS scores measuring changes in headache and dizziness (p<0.001, r=0.34; p=0.01, r=0.20 respectively) significantly increased. There was no significant correlation between depression-related symptoms and balance performance (p=0.093, r=0.13). In adolescents, as depression-related symptoms increased parent reported executive function decreased (p<0.001, r=0.46). Those who reported a concussion history reported significantly more depressive-related symptoms (p=0.004), concussion symptoms (p=0.004), and mood disturbance (p=0.002). CONCLUSION: This study adds to the current literature surrounding the relationship between concussion and depression by identifying a relationship between depression related symptoms, post-concussion symptoms, and post-concussion clinical assessments.
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