Several training strategies have been suggested and evaluated for their effects on baseball pitching performance and injury risk. There is some data in the current literature which indicates that plyometric based weighted-ball training is effective at altering the kinematics and kinetics of the throwing motion. However, it is unclear whether weighted-ball trained pitchers throw faster with lower joint kinetics than those trained otherwise. PURPOSE: To compare throwing velocity and maximum elbow valgus torque (MEV) between collegiate male baseball pitchers trained with weighted-ball exercises and those without. It was hypothesized that weighted-ball trained pitchers exhibit higher throwing velocity and MEV than pitchers trained without weighted-ball exercises. METHODS: Twenty-one collegiate baseball pitchers participated in this study, 13 of whom trained using weighted baseballs and 9 of whom trained without weighted baseballs as part of their in-season training regimen. After providing written informed consent, each participant threw 15 fastballs while ball speed and MEV were measured using a radar gun and a wearable inertial measuring unit (IMU), respectively. RESULTS: There was no significant difference in ball speed between weighted-ball trained pitchers (36 ± 1 m/s) and non-weighted-ball trained pitchers (35 ± 3 m/s, p = .108). Conversely, weighted-ball pitchers threw with greater MEV (110 ± 28 N⋅m) than non-weighted-ball trained pitchers (52 ± 6 N⋅m, p < 0.001). CONCLUSION: These findings suggest that pitchers who train using weighted-ball exercises throw at ball speeds comparable to those who do not but may do so at a higher risk of a pitching-related elbow injury.